Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-[4-(4-Benzyloxyphenyl)butyl]imidazole → 1-[4-(4-Hydroxyphenyl)butyl]imidazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-[4-(4-Benzyloxyphenyl)butyl]imidazole | HCID 22009759 | — |
| 촉매 | HCID 178418390 | HCID 178418390 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 1-[4-(4-Hydroxyphenyl)butyl]imidazole | HCID 22009664 | 94% |
반응 단계
A mixture of 1-[4-(4-benzyloxyphenyl)butyl]imidazole (13.0 g), palladium-carbon (5%, 10.0 g) and ethanol (100 ml) was subjected to catalitic hydrogenation at room temperature under 1 atom. The catalyst was filtered off, and the filtrate was concentrated to give 1-[4-(4-hydroxyphenyl)butyl]imidazole (8.58 g, 94%). Recrystallization from ethyl acetate-hexane gave colorless prisms, mp 124-125° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06211215B1 |
| 출처 데이터셋 | uspto-grants-2001_04 |
| ORD ID | ord-5079aab069a146f19020ca3821f237c1 |
| 출처 메모 | uspto-grants-2001_04 |