Imidazole → 1-[3-(3-Chloro-4-methoxymethoxyphenyl)propyl]imidazole

HRID 322339노트

반응식

HRID 322339 반응식
CS(O[CH2:6][CH2:7][CH2:8][C:9]1[CH:14]=[CH:13][C:12]([O:15][CH2:16][O:17][CH3:18])=[C:11]([Cl:19])[CH:10]=1)(=O)=O.[NH:20]1[CH:24]=[CH:23][N:22]=[CH:21]1>>[Cl:19][C:11]1[CH:10]=[C:9]([CH2:8][CH2:7][CH2:6][N:20]2[CH:24]=[CH:23][N:22]=[CH:21]2)[CH:14]=[CH:13][C:12]=1[O:15][CH2:16][O:17][CH3:18]

참가 물질

3

반응물 2

HCID 795ImidazoleHCID 220095913-(3-Chloro-4-methoxymethoxyphenyl)propyl methanesulfonate

생성물 1

HCID 220096291-[3-(3-Chloro-4-methoxymethoxyphenyl)propyl]imidazole수율 65%

실험 절차

In substantially the same manner as in Reference Example 88, 3-(3-chloro-4-methoxymethoxyphenyl)propyl methanesulfonate was reacted with imidazole to obtain 1-[3-(3-chloro-4-methoxymethoxyphenyl)propyl]imidazole as an oil. The yield was 65%.

출처 및 근거

ORD 기록
ord-4b522f19d3ef45cd8a013c2730ad374e
출처 데이터셋
uspto-grants-2001_04
특허 번호
US06211215B1

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