Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Thionyl Chloride → 1-(2-Chloroethoxy)-4-nitrobenzene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 반응물 | 2-(4-Nitrophenoxy)ethanol | HCID 85381 | — |
| 생성물 | 1-(2-Chloroethoxy)-4-nitrobenzene | HCID 2764587 | — |
반응 단계
4-Nitro-(2-Hydroxyethoxy)benzene (1.13 g, 6.2 mmol) in thionyl chloride (10 mL) is heated at reflux for 3 hours then concentrated in vacuo. After cooling the residue in an ice water bath, saturated aqueous sodium bicarbonate is added and the precipitate collected, rinsed with water, and dried to give 4-nitro-(2-chloroethoxy)benzene (909 mg).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06211365B1 |
| 출처 데이터셋 | uspto-grants-2001_04 |
| ORD ID | ord-c4e1a6c1250a445185e50851c001f832 |
| 출처 메모 | uspto-grants-2001_04 |