2,4-Dichlorophenylacetic acid → 2-[(2,4-Dichlorophenyl)acetamido]butyric acid isobutyl ester

반응식

[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[CH2:9][C:10]([OH:12])=O.[NH2:13][CH:14]([CH2:22][CH3:23])[C:15]([O:17][CH2:18][CH:19]([CH3:21])[CH3:20])=[O:16]>>[CH2:18]([O:17][C:15](=[O:16])[CH:14]([NH:13][C:10](=[O:12])[CH2:9][C:3]1[CH:4]=[CH:5][C:6]([Cl:8])=[CH:7][C:2]=1[Cl:1])[CH2:22][CH3:23])[CH:19]([CH3:20])[CH3:21]

참가 물질

반응물 2

HCID 882092,4-Dichlorophenylacetic acid

HCID 13743360Isobutyl 2-aminobutyrate

생성물 1

HCID 541261332-[(2,4-Dichlorophenyl)acetamido]butyric acid isobutyl ester

실험 절차

Following General Procedure I′ above and using 2,4-dichlorophenylacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure J′ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

후처리

customprepared

출처 및 근거

ORD 기록: ord-41d3eb134f3a4bb2aebdaed01527a34a
출처 데이터셋: uspto-grants-2001_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06211235B1

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