Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl cyanoacetate → methyl (E)-3-(2,4-dibenzyloxyphenyl)-2-cyanoacrylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl cyanoacetate | HCID 7747 | — |
| 반응물 | Piperidine | HCID 8082 | — |
| 반응물 | 2,4-Bis(benzyloxy)benzaldehyde | HCID 1809080 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | methyl (E)-3-(2,4-dibenzyloxyphenyl)-2-cyanoacrylate | HCID 86756581 | — |
반응 단계
A mixture of 2,4-dibenzyloxybenzaldehyde (1 g), methyl cyanoacetate (0.27 mL), piperidine (0.1 mL) and ethanol (30 mL) is stirred at ambient temperature for 20 minutes and the solvent is removed under reduced pressure. The residue is recrystallized from ethanol to give methyl (E)-3-(2,4-dibenzyloxyphenyl)-2-cyanoacrylate as a yellow solid (400 mg).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06211234B1 |
| 출처 데이터셋 | uspto-grants-2001_04 |
| ORD ID | ord-c5088d268910443a81fef21ea2bc3c30 |
| 출처 메모 | uspto-grants-2001_04 |