Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Triethylamine → 3-Iodo-N-methoxy-N-methylbenzamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | 3-Iodobenzoyl chloride | HCID 74378 | — |
| 반응물 | 1-Methoxymethanamine | HCID 17778177 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 3-Iodo-N-methoxy-N-methylbenzamide | HCID 22322052 | — |
반응 단계
A stirred solution of N-methoxymethylamine (3.47 g) and triethylamine (10.4 mL) in dichloromethane (100 mL) at 5° C. is treated dropwise with 3-iodobenzoyl chloride (9.8 g). The reaction mixture is stirred at room temperature for 2 hours, washed twice with water (70 mL), dried over magnesium sulphate, and evaporated to give N-methoxy-N-methyl-3-iodobenzamide (9.8 g) as a brown oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06211234B1 |
| 출처 데이터셋 | uspto-grants-2001_04 |
| ORD ID | ord-e480a71bec5f485ab375837bfa47cb72 |
| 출처 메모 | uspto-grants-2001_04 |