2-Bromophenyl isocyanate → sb 225002

HRID 323035노트

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HRID 323035 반응식
[OH:1][C:2]1[CH:8]=[C:7]([N+:9]([O-:11])=[O:10])[CH:6]=[CH:5][C:3]=1[NH2:4].[Br:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=1[N:19]=[C:20]=[O:21]>>[OH:1][C:2]1[CH:8]=[C:7]([N+:9]([O-:11])=[O:10])[CH:6]=[CH:5][C:3]=1[NH:4][C:20]([NH:19][C:14]1[CH:15]=[CH:16][CH:17]=[CH:18][C:13]=1[Br:12])=[O:21]

참가 물질

3

반응물 2

HCID 1370972-Bromophenyl isocyanateHCID 49847212-Amino-5-Nitrophenol

생성물 1

HCID 3854666sb 225002수율 47%

실험 절차

N-(2-Hydroxy-4-nitrophenyl)-N′-(2-bromophenyl)urea was prepared from 2-hydroxy 4-nitro aniline (500 mg, 3.24 mmol) and 2-bromophenyl isocyanate (3.24 mmol) according to the procedure in General Method B. The product was purified by dilution with methylene chloride and precipitation with hexanes. Filtering afforded the title compound (530 mg, 47%). EI-MS m/z 350 (M−H)−

후처리

  1. customThe product was purified by dilution with methylene chloride and precipitation with hexanes
  2. filtrationFiltering

출처 및 근거

ORD 기록
ord-9da31bd23ecb43afab7932426795d47f
출처 데이터셋
uspto-grants-2001_04
특허 번호
US06211373B1

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