2-Bromophenyl isocyanate → (2-Bromophenyl)urea

반응식

OC1C=C(C=CC=1[NH2:11])C(O)=O.[Br:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=1[N:19]=[C:20]=[O:21]>>[Br:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=1[NH:19][C:20](=[O:21])[NH2:11]

참가 물질

반응물 2

HCID 1370972-Bromophenyl isocyanate

HCID 1375664-Amino-3-hydroxybenzoic acid

생성물 1

HCID 139386(2-Bromophenyl)urea

실험 절차

The urea was prepared from 3-hydroxy 4-amino benzoic acid (3.69 g, 24 mmol) and 2-bromo phenyl isocyanate (24 mmol) by general Method B. It was purified by dilution of the DMF solution with methylene chloride and precipitation with hexane (4.0 g, 48%). EI-MS m/z 351 (M+H)+

후처리

customIt was purified by dilution of the DMF solution with methylene chloride and precipitation with hexane (4.0 g, 48%)

출처 및 근거

ORD 기록: ord-3d326b6184b0452ab8bb3c8ce11a7ef8
출처 데이터셋: uspto-grants-2001_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06211373B1

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