4-Cyanobenzaldehyde → [4-(Aminomethyl)phenyl]methanol

HRID 32319

반응식

HRID 32319 반응식
[C:1]([C:3]1[CH:10]=[CH:9][C:6]([CH:7]=[O:8])=[CH:5][CH:4]=1)#[N:2].C(OC1C=C(C=C(OCC2C=CC=CC=2)C=1)CN)C1C=CC=CC=1>>[OH:8][CH2:7][C:6]1[CH:9]=[CH:10][C:3]([CH2:1][NH2:2])=[CH:4][CH:5]=1

참가 물질

3

반응물 2

HCID 660424-CyanobenzaldehydeHCID 15505554[3,5-Bis(benzyloxy)benzyl]amine hydrochloride

생성물 1

HCID 6496943[4-(Aminomethyl)phenyl]methanol수율 46%

실험 절차

This compound was prepared by reduction of 4-cyanobenzaldehyde according to the procedure described in preparation of 3,5-dibenzyloxybenzylamine. Yield was 46%: MP 102-123° C.; 1H NMR (Acetone-d6, 500 MHz) 7.27 (m, complex 4H), 4.58 (s, 2H), 3.72 (s, 2H), 3.69 (s, 1H) 2.77 (br, 1H), 2.45 (br, 1H);

출처 및 근거

ORD 기록
ord-b108a33eb56d42ed8a2fc4baf57a0a48
출처 데이터셋
uspto-grants-2008_09
특허 번호
US07427608B2

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