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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 323347생성일: 2026년 10월 25일

3,4,5-Trimethoxybenzoyl-3-phenyl-3-(2-methanesulfonyloxyethyl)pyrrolidine → 1-(3,4,5-trimethoxybenzoyl)-3-(2-(4-(1-(4-oxopentyl)-1H-benzimidazol-2-yl-amino)piperidin-1-yl)ethyl)-3-phenylpyrrolidine

https://huagongshe.com/reaction/323347

반응식

참여 물질

역할이름HCID투입량
반응물3,4,5-Trimethoxybenzoyl-3-phenyl-3-(2-methanesulfonyloxyethyl)pyrrolidineHCID 18464630—
반응물(1-(4-Oxopentyl)-1H-benzimidazol-2-yl)(piperidin-4-yl)amine Hydriodic Acid SaltHCID 86756597—
생성물1-(3,4,5-trimethoxybenzoyl)-3-(2-(4-(1-(4-oxopentyl)-1H-benzimidazol-2-yl-amino)piperidin-1-yl)ethyl)-3-phenylpyrrolidineHCID 20642297—

반응 단계

Prepare by the method of Example 1.6 using 1-(3,4,5-trimethoxybenzoyl)-3-phenyl-3-(2-methanesulfonyloxyethyl)pyrrolidine (prepared from (−)-3-phenyl-3-(2-hydroxyethyl)pyrrolidine (R,R)-di-p-anisoyltartaric acid salt) and (1-(4-oxopentyl)-1H-benzimidazol-2-yl)(piperidin-4-yl)amine hydriodic acid salt to give the title compound.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US06211199B1
출처 데이터셋uspto-grants-2001_04
ORD IDord-33c96756594a48d8bf9d375bc2f4b4a1
출처 메모uspto-grants-2001_04