Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → Acridine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Isatin | HCID 7054 | — |
| 반응물 | 3-Chloroacridinecarboxylic acid | HCID 18006790 | — |
| 용매 | Water | HCID 962 | — |
| 용매 | Potassium Hydroxide | HCID 14797 | — |
| 생성물 | Acridine | HCID 9215 | — |
반응 단계
3-Chloroacridinecarboxylic acid. The isatin product from step (a) was refluxed in 300 mL of 10% KOH solution in water for ca. 48 h. The solution was cooled and acidified to pH 2-3 with HCl. The yellow solid was suction filtered after 1 h and then washed with water. The solid was air-dried over night, washed with CH2Cl2 and then air-dried yielding 23.76 g of the acridine acid. 1H NMR (DMSO-d6) 8 7.72-8.30 (m, 7H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06218137B1 |
| 출처 데이터셋 | uspto-grants-2001_04 |
| ORD ID | ord-6023d4cdbeb04b639c5e35e39eab9645 |
| 출처 메모 | uspto-grants-2001_04 |