Acetone → HCID 69313249, 화합물
반응식
[Cl:1][C:2]1[C:10]2[C:5](=[CH:6][C:7]([C:11]([NH:13][CH:14]([C:27]3[CH:32]=[CH:31][CH:30]=[CH:29][N:28]=3)[CH2:15][O:16][CH2:17][CH:18]3[CH2:23][CH2:22][N:21]([CH:24]([CH3:26])[CH3:25])[CH2:20][CH2:19]3)=[O:12])=[CH:8][CH:9]=2)[NH:4][CH:3]=1.CC(C)=O>>[ClH:1].[Cl:1][C:2]1[C:10]2[C:5](=[CH:6][C:7]([C:11]([NH:13][CH:14]([C:27]3[CH:32]=[CH:31][CH:30]=[CH:29][N:28]=3)[CH2:15][O:16][CH2:17][CH:18]3[CH2:19][CH2:20][N:21]([CH:24]([CH3:26])[CH3:25])[CH2:22][CH2:23]3)=[O:12])=[CH:8][CH:9]=2)[NH:4][CH:3]=1참가 물질
3
실험 절차
Using deprotection method A, 3-chloro-N-[1-(2-pyridinyl)-2-(1-isopropylpiperidin-4-ylmethoxy)ethyl]-1H-indole-6-carboxamide (105 mg, 0.25 mmol) and acetone (1.2 mL, 16.8 mmol) afforded 110 mg (96%) of the title compound.
출처 및 근거
- ORD 기록
- ord-93a9cac0e14348288f94a2a269732aa8
- 출처 데이터셋
- uspto-grants-2008_09
- 특허 번호