HCID 85980352, 화합물 → 1-Phenyl-4-(pyridin-4-yl)butylamine

반응식

[H][H].[C:3]1([C:9](=[N:19]O)[CH2:10][CH2:11][CH2:12][C:13]2[CH:18]=[CH:17][N:16]=[CH:15][CH:14]=2)[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1>>[C:3]1([CH:9]([NH2:19])[CH2:10][CH2:11][CH2:12][C:13]2[CH:14]=[CH:15][N:16]=[CH:17][CH:18]=2)[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1

참가 물질

반응물 2

HCID 85980352HCID 85980352, 화합물

HCID 178418361HCID 178418361, 화합물

생성물 1

HCID 655846421-Phenyl-4-(pyridin-4-yl)butylamine수율 88.4%

실험 절차

Using deprotection method A under 4.1 bar (60 psig) of hydrogen, 1-phenyl-4-(pyridin-4-yl)butan-1-one oxime (1.6 g, 6.5 mmol) afforded 1.3 g (87%) of the title compound.

출처 및 근거

ORD 기록: ord-dc20a0ed308e4c96af8685a6c280c0d1
출처 데이터셋: uspto-grants-2008_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07427632B2

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