1-(2,5-Difluoro-phenyl)-cyclopropanecarbonyl chloride → HCID 178507152, 화합물

HRID 32503

반응식

HRID 32503 반응식
[F:1][C:2]1[CH:7]=[CH:6][C:5]([F:8])=[CH:4][C:3]=1[C:9]1([C:12](Cl)=[O:13])[CH2:11][CH2:10]1.[NH2:15][C:16]1[N:21]([C:22]2[CH:27]=[CH:26][C:25]([NH2:28])=[CH:24][CH:23]=2)[CH2:20][N:19]=[C:18]2[O:29][CH:30]=[CH:31][C:17]=12>>[NH2:15][C:16]1[N:21]([C:22]2[CH:23]=[CH:24][C:25]([NH:28][C:12]([C:9]3([C:3]4[CH:4]=[C:5]([F:8])[CH:6]=[CH:7][C:2]=4[F:1])[CH2:11][CH2:10]3)=[O:13])=[CH:26][CH:27]=2)[CH2:20][N:19]=[C:18]2[O:29][CH:30]=[CH:31][C:17]=12

참가 물질

3

반응물 2

HCID 834119541-(2,5-Difluoro-phenyl)-cyclopropanecarbonyl chlorideHCID 178507147HCID 178507147, 화합물

생성물 1

HCID 178507152HCID 178507152, 화합물

실험 절차

The compound was prepared following the procedure described in Example 474, using 1-(2,5-Difluoro-phenyl)-cyclopropanecarbonyl chloride as the acid chloride of choice, and 4-Amino-3-(4-aminophenyl)furo[2,3-d]pyrimidine (9) as the diamine of choice. MS(ES) m/e 407 [M+H]+.

후처리

  1. customThe compound was prepared

출처 및 근거

ORD 기록
ord-a2a5cdbcff964687b2196f46bfc49a30
출처 데이터셋
uspto-grants-2008_09
특허 번호
US07427623B2

연결된 노트

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