Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Boron tribromide → 1,3-Benzenediol, 5-chloro-
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Boron tribromide | HCID 25134 | — |
| 반응물 | 1-Chloro-3,5-dimethoxybenzene | HCID 81502 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 1,3-Benzenediol, 5-chloro- | HCID 94554 | 207.5% |
반응 단계
BBr3 (26 mL; 0.275 mmol) was added to a solution of chloro-3,5-dimethyoxybenzene (10 g; 30 mmol) in CH2Cl2 (100 mL) at −70° C. The cooling bath was removed and the solution was stirred at room temperature for 4 days. After re-cooling to −70° C., MeOH was added (150 mL). After evaporation of the solvent, toluene was added and removed in vacuo. Purification by kugelrohr distillation afforded 9 g (100%) of the sub-title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06221898B1 |
| 출처 데이터셋 | uspto-grants-2001_04 |
| ORD ID | ord-5c2301bc40c447f2a2c5833beed983cc |
| 출처 메모 | uspto-grants-2001_04 |