methyl (2S)-2-amino-4-(methylsulfanyl)butanoate → [4-Hydroxymethyl-2-phenylbenzoyl]methionine methyl ester

반응식

[OH:1][CH2:2][C:3]1[CH:11]=[CH:10][C:6]([C:7]([OH:9])=O)=[C:5]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[CH:4]=1.[CH3:18][O:19][C:20](=[O:27])[C@H:21]([CH2:23][CH2:24][S:25][CH3:26])[NH2:22]>>[CH3:18][O:19][C:20](=[O:27])[C@H:21]([CH2:23][CH2:24][S:25][CH3:26])[NH:22][C:7](=[O:9])[C:6]1[CH:10]=[CH:11][C:3]([CH2:2][OH:1])=[CH:4][C:5]=1[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1

참가 물질

반응물 2

HCID 64684methyl (2S)-2-amino-4-(methylsulfanyl)butanoate

HCID 234364204-Hydroxymethyl-2-phenylbenzoic acid

생성물 1

HCID 20622833[4-Hydroxymethyl-2-phenylbenzoyl]methionine methyl ester

실험 절차

The resultant product from Example 16C is coupled to methionine methyl ester according to the procedure of Example 1C to give the title compound.

출처 및 근거

ORD 기록: ord-fb31e3c79bc846f092dcd7a738749e90
출처 데이터셋: uspto-grants-2001_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06221865B1

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