Diethyl Ether → 74137-64-7
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[CH3:1][CH:2]([C@@:4]1([NH:26][C:27]([C@H:29]2[CH:44]=[C:43]3[C@@H:32]([CH2:33][C:34]4[C:42]5[C:37](=[CH:38][CH:39]=[CH:40][C:41]=53)[NH:36][CH:35]=4)[N:31]([CH3:45])[CH2:30]2)=[O:28])[O:17][C@:16]2([OH:18])[N:7]([C@@H:8]([CH2:19][C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)[C:9]([N:11]3[C@H:15]2[CH2:14][CH2:13][CH2:12]3)=[O:10])[C:5]1=[O:6])[CH3:3].[CH3:46][S:47]([OH:50])(=[O:49])=[O:48].C(OCC)C>C(O)C>[CH3:3][CH:2]([C@@:4]1([NH:26][C:27]([C@@H:29]2[CH:44]=[C:43]3[C@H:32]([CH2:33][C:34]4[C:42]5[C:37](=[CH:38][CH:39]=[CH:40][C:41]=53)[NH:36][CH:35]=4)[N:31]([CH3:45])[CH2:30]2)=[O:28])[O:17][C@:16]2([OH:18])[N:7]([C@H:8]([CH2:19][C:20]3[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=3)[C:9]([N:11]3[C@H:15]2[CH2:14][CH2:13][CH2:12]3)=[O:10])[C:5]1=[O:6])[CH3:1].[CH3:46][S:47]([OH:50])(=[O:49])=[O:48]참가 물질
5
실험 절차
Ergocristinine (1.25 g; 0.05 mmoles) was dissolved in absolute ethanol (25 ml), containing methanesulfonic acid (0.15 ml; 2.31 mmoles). After clarifying, the solution was slowly poured into absolute diethylether (350 ml) while stirring. The precipitated salt was filtered off and dried in vacuo. Ergocristinine methanesulfonate (1.40 g; 96.4% of the theory) with a melting point of 170°-180° C. was obtained.