Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → N-Acetyl-S-methyl-L-cysteine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Acetic Anhydride | HCID 7918 | — |
| 반응물 | (-)-S-Methyl-L-cysteine | HCID 24417 | — |
| 용매 | Sodium Hydroxide | HCID 14798 | — |
| 생성물 | N-Acetyl-S-methyl-L-cysteine | HCID 13893975 | 89.7% |
반응 단계
A solution of 13.5 g (100 mmole) of S-methyl-L-cysteine dissolved in 210 ml of 1 N sodium hydroxide solution was ice cooled and 10.4 ml (110 mmole) of acetic anhydride was added thereto dropwise. After 2.0 hours at room temperature, the mixture was acidified to pH 1.0 with 6 N hydrochloric acid and extracted with ethyl acetate. The extract was dried over anhydrous magnesium sulfate and concentrated in vacuo to give 15.9 g (89.6% yield) of S-methyl-N-acetyl-L-cysteine as an oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04440788 |
| 출처 데이터셋 | uspto-grants-1984_04 |
| ORD ID | ord-1289b227d0be43a18e1a3d5cb961e5a3 |
| 출처 메모 | uspto-grants-1984_04 |