Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 325358생성일: 2026년 10월 25일
(+-)-3,4-Dimethoxyamphetamine → 3-[3-(3,4-Dimethoxyphenyl)-2-propylamino]1,2-propanediol
https://huagongshe.com/reaction/325358
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | (+-)-3,4-Dimethoxyamphetamine | HCID 8423 | — |
| 반응물 | Glycidol | HCID 11164 | — |
| 용매 | Isopropanol | HCID 3776 | — |
| 생성물 | 3-[3-(3,4-Dimethoxyphenyl)-2-propylamino]1,2-propanediol | HCID 53772682 | — |
반응 단계
A solution of 3-(3,4-dimethoxyphenyl)-2-propylamine (20.0 g., 0.10 m.) in isopropanol (20 ml.) is heated to 50° C. while a solution of glycidol (5.0 g., 0.067 m.) in isopropanol (5ml.) is added over 15 minutes. The mixture is stirred at 50° C. for 0.5 hours and then at 70° C. for 16 hours. The solvent is concentrated under reduced pressure and the residue is chromatographed on silica gel, eluting with 10% MeOH-CHCl3 saturated with NH3 to yield (I) weighing 14.37 g. (80%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04440774 |
|---|
| 출처 데이터셋 | uspto-grants-1984_04 |
|---|
| ORD ID | ord-92a35f2d760a45c38edb2edad7e594d5 |
|---|
| 출처 메모 | uspto-grants-1984_04 |
|---|
