Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 2-Amino-3-(trifluoromethyl)benzoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Hydrogen Peroxide | HCID 784 | — |
| 반응물 | 7-Trifluoromethylisatin | HCID 604575 | — |
| 용매 | Water | HCID 962 | — |
| 용매 | Sodium Hydroxide | HCID 14798 | — |
| 생성물 | 2-Amino-3-(trifluoromethyl)benzoic acid | HCID 604569 | — |
반응 단계
7-Trifluoromethylisatin (10 g, 46 mmol) was dissolved in 5% sodium hydroxide solution (83 ml). To this was added dropwise over 30 minutes a solution of 50% hydrogen peroxide (7.4 ml) in water (4.6 ml); the temperature rose to 50°. The solution was stirred an additional 30 minutes, acidified (conc. HCl) to pH 1-2, and the tan product was filtered.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04440941 |
| 출처 데이터셋 | uspto-grants-1984_04 |
| ORD ID | ord-c4d53f54931b4664aa89f8d725f00624 |
| 출처 메모 | uspto-grants-1984_04 |