Timonacic → 3-[3-(4-Pentadecenylamino)benzoyl]-4-carboxythiazolidine

HRID 325570

반응식

HRID 325570 반응식
[CH2:1]([NH:16][C:17]1[CH:18]=[C:19]([CH:32]=[CH:33][CH:34]=1)[C:20]([N:22]1[CH:26]([C:27]([O:29]CC)=[O:28])[CH2:25][S:24][CH2:23]1)=[O:21])[CH2:2][CH2:3][CH:4]=[CH:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH3:15].S1CC(C(O)=O)NC1>C(=O)(O)[O-].[Na+].CC(C)=O>[CH2:1]([NH:16][C:17]1[CH:18]=[C:19]([CH:32]=[CH:33][CH:34]=1)[C:20]([N:22]1[CH:26]([C:27]([OH:29])=[O:28])[CH2:25][S:24][CH2:23]1)=[O:21])[CH2:2][CH2:3][CH:4]=[CH:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH3:15]

참가 물질

4

반응물 2

HCID 9934TimonacicHCID 538623083-[3-(4-Pentadecenylamino)benzoyl]-4-carboethoxythiazolidine

생성물 1

HCID 537972693-[3-(4-Pentadecenylamino)benzoyl]-4-carboxythiazolidine

시약·촉매·용매 1

HCID 86737261Acetone sodium bicarbonate용매

실험 절차

By means of the alkaline hydrolysis method of Example 2 the ethyl ester of Example 548 is converted to the subject carboxylic acid. This acid is also prepared using the procedure of Example 548 except that the acylation of the thiazolidine-4-carboxylic acid is carried out in aqueous acetone sodium bicarbonate solution.

후처리

  1. customThis acid is also prepared

출처 및 근거

ORD 기록
ord-df868f938c0f45f6a856aa523a785110
출처 데이터셋
uspto-grants-1984_04
특허 번호
US04440940

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