Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrazine hydrate (1:1) → 4-[3-Aminopropoxy]-N,N-dimethylbenzeneethanamine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrazine hydrate (1:1) | HCID 24654 | — |
| 반응물 | 2-[3-[4-[2-(Dimethylamino)ethyl]phenoxy]propyl]-1H-isoindole-1,3-(2H)-dione | HCID 21297567 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 4-[3-Aminopropoxy]-N,N-dimethylbenzeneethanamine | HCID 21297555 | — |
반응 단계
2-[3-[4-[2-(Dimethylamino)ethyl]phenoxy]propyl]-1H-isoindole-1,3-(2H)-dione (2.1 g) and hydrazine hydrate (1.2 ml) were heated at reflux in ethanol for 4 h. The solvent was evaporated and the residue was distilled to give the title compound as a clear yellow oil b.p. 170° (0.1 mm). TLC silica; ethyl acetate:water:isopropanol:0.88 ammonia 25:8:15:2; Rf 0.35.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04442110 |
| 출처 데이터셋 | uspto-grants-1984_04 |
| ORD ID | ord-a7dd293f0c334bf2a6bbdb2de53afc76 |
| 출처 메모 | uspto-grants-1984_04 |