4-methoxy-N,6-dimethylpyrimidin-2-amine → N-[N-(4-methoxy-6-methylpyrimidin-2-yl)-N-methylaminocarbonyl]-2-thiophene sulfonamide
반응식
[CH3:1][NH:2][C:3]1[N:8]=[C:7]([O:9][CH3:10])[CH:6]=[C:5]([CH3:11])[N:4]=1.[S:12]1[CH:16]=[CH:15][CH:14]=[C:13]1[S:17]([N:20]=[C:21]=[O:22])(=[O:19])=[O:18]>C(#N)C>[CH3:10][O:9][C:7]1[CH:6]=[C:5]([CH3:11])[N:4]=[C:3]([N:2]([CH3:1])[C:21]([NH:20][S:17]([C:13]2[S:12][CH:16]=[CH:15][CH:14]=2)(=[O:18])=[O:19])=[O:22])[N:8]=1참가 물질
4
실험 절차
To a mixture, 1.5 g of 2-methylamino-4-methoxy-6-methylpyrimidine in 50 ml of acetonitrile is added 1.9 g of 2-thiophenesulfonyl isocyanate. Filtration affords N-[N-(4-methoxy-6-methylpyrimidin-2-yl)-N-methylaminocarbonyl]-2-thiophene sulfonamide.
후처리
- filtrationFiltration
출처 및 근거
- ORD 기록
- ord-e9e350dd44434e4aa93f50cfff406e89
- 출처 데이터셋
- uspto-grants-1984_04
- 특허 번호
- US04443244
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