Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Propargyl bromide → 2-(Prop-2-yn-1-yloxy)benzene-1-sulfonamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Propargyl bromide | HCID 7842 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 2-Hydroxybenzene-1-sulfonamide | HCID 637546 | — |
| 용매 | Methyl Ethyl Ketone | HCID 6569 | — |
| 생성물 | 2-(Prop-2-yn-1-yloxy)benzene-1-sulfonamide | HCID 13472945 | — |
반응 단계
A mixture of 35 g of 2-hydroxyphenylsulfonamide, 55.2 g of potassium carbonate, 15.5 ml of propargyl bromide and 1000 ml of ethyl methyl ketone is refluxed for 1.5 hours; it is then cooled, filtered, and concentrated by evaporation. The yield after recrystallisation of the residue from ethyl acetate is 30 g of 2-propargyloxyphenylsulfonamide, m.p. 143°-145° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04443243 |
| 출처 데이터셋 | uspto-grants-1984_04 |
| ORD ID | ord-47781081ac0a4e7d88cd65dc00613ba4 |
| 출처 메모 | uspto-grants-1984_04 |