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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 326174생성일: 2026년 10월 24일

Water → 2-{2-[3-Methoxy-4-(2-hydroxy-3-methacryloyloxypropyloxy)-phenyl]-ethenyl}-quinoline

https://huagongshe.com/ko/reaction/326174

반응식

참여 물질

역할이름HCID투입량
반응물WaterHCID 962—
반응물Glycidyl methacrylateHCID 7837—
반응물2-[2-(4-Hydroxy-3-methoxyphenyl)-ethenyl]-quinolineHCID 623970—
촉매Tetrabutylammonium ChlorideHCID 70681—
용매DimethylacetamideHCID 31374—
생성물2-{2-[3-Methoxy-4-(2-hydroxy-3-methacryloyloxypropyloxy)-phenyl]-ethenyl}-quinolineHCID 5432794050%

반응 단계

In 5 cm3 of N,N-dimethylacetamide, 2.77 g of the produced quinoline derivative was dissolved and 1.42 g of glycidyl methacrylate and 0.10 g of tetrabutylammonium chloride were added thereto. The resultant mixture was reacted by maintaining it at 90° to 100° C. for 5 hours. The reaction product was mixed with water. The oily substance separated consequently was extracted via ethyl acetate, washed thoroughly with water, and dried. The dry product was distilled to expel the solvent and then separated and purified by silica gel chromatography, to afford 2-{2-[3-methoxy-4-(2-hydroxy-3-methacryloyloxypropyloxy)-phenyl]-ethenyl}-quinoline in a yield of 50%. When this product was recrystallized via ethyl acetatehexane, there was obtained a pure product having a melting point of 119° C. It was identified by elementary analysis and infrared absorption spectrometry.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US04444868
출처 데이터셋uspto-grants-1984_04
ORD IDord-937b96f9883c4dc3af7a5c24d204bfd7
출처 메모uspto-grants-1984_04