Cyclopropanecarboxaldehyde → [5-(7-amino[1,3]thiazolo[5,4-d]pyrimidin-2-yl)-1-methyl-4-phenyl-1H-imidazol-2-yl](cyclopropyl)methyl dimethylcarbamate
반응식
[CH3:1][N:2]([CH3:35])[C:3](=[O:34])[O:4][CH:5]([C:12]1[N:13]([CH3:33])[C:14]([C:23]2[S:24][C:25]3[N:26]=[CH:27][N:28]=[C:29]([NH2:32])[C:30]=3[N:31]=2)=[C:15]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[N:16]=1)[C:6]1[CH:11]=CC=C[CH:7]=1.C1(C=O)CC1>>[CH3:35][N:2]([CH3:1])[C:3](=[O:34])[O:4][CH:5]([C:12]1[N:13]([CH3:33])[C:14]([C:23]2[S:24][C:25]3[N:26]=[CH:27][N:28]=[C:29]([NH2:32])[C:30]=3[N:31]=2)=[C:15]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[N:16]=1)[CH:6]1[CH2:7][CH2:11]1참가 물질
3
반응물 2
생성물 1
실험 절차
The title compound was prepared by a similar process to that described for Intermediate 97 but using cyclopropanecarboxaldehyde in place of benzaldehyde. Colourless gum (14 mg, 68%);
출처 및 근거
- ORD 기록
- ord-62ff8a8fefb74dbfb45c5961c9d8ad50