Thionyl Chloride → 5-Hexylthiophene-2-carboxylic acid chloride

반응식

[CH2:1]([C:7]1[S:11][C:10]([C:12]([OH:14])=O)=[CH:9][CH:8]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6].S(Cl)([Cl:17])=O>>[CH2:1]([C:7]1[S:11][C:10]([C:12]([Cl:17])=[O:14])=[CH:9][CH:8]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6]

참가 물질

반응물 2

HCID 24386Thionyl Chloride

HCID 131282695-Hexyl-2-thiophenecarboxylic acid

생성물 1

HCID 131282725-Hexylthiophene-2-carboxylic acid chloride

반응 조건

온도: 80 °C

실험 절차

10 ml of thionyl chloride was added to 1.0 g (4.72×10-3 ml) of 5-hexylthiophene-2-carboxylic acid, followed by stirring for 4 hours under heating at 80° C. and removal of excessive thionyl chloride by reduced-pressure distillation to obtain 5-hexylthiophene-2 -carboxylic chloride.

후처리

customremoval of excessive thionyl chloride
distillationby reduced-pressure distillation

출처 및 근거

ORD 기록: ord-428139fe7d494ec893429a8e138d97bd
출처 데이터셋: uspto-grants-1993_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05268123

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