3-Methylbutanal → 1-[5-(7-amino[1,3]thiazolo[5,4-d]pyrimidin-2-yl)-1-methyl-4-phenyl-1H-imidazol-2-yl]-3-methylbutyl dimethylcarbamate

HRID 32623

반응식

HRID 32623 반응식
[CH3:1][N:2]([CH3:35])[C:3](=[O:34])[O:4][CH:5]([C:12]1[N:13]([CH3:33])[C:14]([C:23]2[S:24][C:25]3[N:26]=[CH:27][N:28]=[C:29]([NH2:32])[C:30]=3[N:31]=2)=[C:15]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[N:16]=1)[C:6]1C=CC=CC=1.[CH:36](=O)[CH2:37][CH:38](C)C>>[CH3:1][N:2]([CH3:35])[C:3](=[O:34])[O:4][CH:5]([C:12]1[N:13]([CH3:33])[C:14]([C:23]2[S:24][C:25]3[N:26]=[CH:27][N:28]=[C:29]([NH2:32])[C:30]=3[N:31]=2)=[C:15]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[N:16]=1)[CH2:6][CH:37]([CH3:38])[CH3:36]

참가 물질

3

반응물 2

HCID 115523-MethylbutanalHCID 69197371[5-(7-Amino[1,3]thiazolo[5,4-d]pyrimidin-2-yl)-1-methyl-4-phenyl-1H-imidazol-2-yl](phenyl)methyl dimethylcarbamate

생성물 1

HCID 691963891-[5-(7-amino[1,3]thiazolo[5,4-d]pyrimidin-2-yl)-1-methyl-4-phenyl-1H-imidazol-2-yl]-3-methylbutyl dimethylcarbamate

실험 절차

The title compound was prepared by a similar process to that described for Intermediate 97 but using isovaleraldehyde in place of benzaldehyde. Pale yellow oil (54 mg, 77%);

출처 및 근거

ORD 기록
ord-15f4e689197a4464b42bda873f57f11a
출처 데이터셋
uspto-grants-2008_09
특허 번호
US07427616B2

연결된 노트

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