1-Propanone, 3-(dimethylamino)-1-phenyl-, hydrochloride (1:1) → 3-(Dimethylamino)-1-phenyl-1-propanone

HRID 326399

반응식

HRID 326399 반응식
Cl.[CH3:2][N:3]([CH3:14])[CH2:4][CH2:5][C:6]([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)=[O:7].C(=O)(O)[O-].[Na+]>ClCCl>[CH3:14][N:3]([CH3:2])[CH2:4][CH2:5][C:6]([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)=[O:7]

참가 물질

4

반응물 2

HCID 928441-Propanone, 3-(dimethylamino)-1-phenyl-, hydrochloride (1:1)HCID 516892Sodium Bicarbonate

생성물 1

HCID 770423-(Dimethylamino)-1-phenyl-1-propanone수율 95.3%

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

3-Dimethylaminopropiophenone hydrochloride (20 g) was treated with aqueous sodium bicarbonate solution in dichloromethane. The layers were separated and the organic phase was dried over anhydrous magnesium sulfate, filtered, and the filtrate was evaporated to provide 15.8 g of 3-dimethylaminopropiophenone.

후처리

  1. customThe layers were separated
  2. dry with materialthe organic phase was dried over anhydrous magnesium sulfate
  3. filtrationfiltered
  4. customthe filtrate was evaporated

출처 및 근거

ORD 기록
ord-8405d6c06e7a480280c47c4f322f1fd8
출처 데이터셋
uspto-grants-1993_12
특허 번호
US05268468

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