6-[4-(3-aminophenyl)-1-methyl-1H-imidazol-5-yl]thieno[2,3-d]pyrimidin-4-amine → 6-[4-(4-Aminophenyl)-1-methyl-1H-imidazol-5-yl]thieno[2,3-d]pyrimidin-4-amine

반응식

NC1C=C(C2N=CN(C)C=2C2SC3N=CN=C(N)C=3C=2)C=CC=1.C1(C(=[N:37][C:38]2[CH:43]=[CH:42][C:41]([C:44]3[N:45]=[CH:46][N:47]([CH3:59])[C:48]=3[C:49]3[S:58][C:52]4[N:53]=[CH:54][N:55]=[C:56]([NH2:57])[C:51]=4[CH:50]=3)=[CH:40][CH:39]=2)C2C=CC=CC=2)C=CC=CC=1.C1(C(=NC2C=CC=CC=2N2C=C(C3(N)NC=NC4SC=CC3=4)N(C)C2)C2C=CC=CC=2)C=CC=CC=1>>[NH2:37][C:38]1[CH:43]=[CH:42][C:41]([C:44]2[N:45]=[CH:46][N:47]([CH3:59])[C:48]=2[C:49]2[S:58][C:52]3[N:53]=[CH:54][N:55]=[C:56]([NH2:57])[C:51]=3[CH:50]=2)=[CH:40][CH:39]=1

참가 물질

반응물 3

HCID 690543996-[4-(3-aminophenyl)-1-methyl-1H-imidazol-5-yl]thieno[2,3-d]pyrimidin-4-amine

HCID 866016426-(4-{4-[(Diphenylmethylene)amino]phenyl}-1-methyl-1H-imidazol-5-yl)thieno[2,3-d]pyrimidin-4-amine2회

HCID 178481200HCID 178481200, 화합물

생성물 1

HCID 691971586-[4-(4-Aminophenyl)-1-methyl-1H-imidazol-5-yl]thieno[2,3-d]pyrimidin-4-amine

실험 절차

The title compound was prepared by a similar process to that described for Intermediate 110 but using 6-(4-{4-[(diphenylmethylene)amino]phenyl}-1-methyl-1H-imidazol-5-yl)thieno[2,3-d]pyrimidin-4-amine (Intermediate 111) in place of 6-(4-{3-[(diphenylmethylene)amino]phenyl}-1-methyl-1H-imidazol-5-yl)thieno[2,3-d]pyrimidin-4-amine (Intermediate 109). Colourless solid (276 mg, 87%);