Indane-1,3-dione, 2-(3-hydroxyphenyl)- → 6-(1,3-Dioxoindan-2-ylidene)-2-oxo-3-(4-amino-3,5-dimethylphenyl)-2,6-dihydrobenzofuran

참여 물질

역할	이름	HCID	투입량
반응물	Indane-1,3-dione, 2-(3-hydroxyphenyl)-	HCID 617192	—
반응물	4-Amino-3,5-dimethylphenyltartronic acid	HCID 20092331	—
용매	Acetic Acid	HCID 176	—
생성물	6-(1,3-Dioxoindan-2-ylidene)-2-oxo-3-(4-amino-3,5-dimethylphenyl)-2,6-dihydrobenzofuran	HCID 20092352	38%

반응 조건

온도	20 °C

반응 단계

4-Amino-3,5-dimethylphenyltartronic acid (2.1 parts), 2-(3-hydroxyphenyl)-1,3-indandione (1.3 parts) and glacial acetic acid (125 parts) were stirred under reflux for 2 hours. The reaction mixture was cooled to 20° C. and the precipitated solid was recovered by filtration, washed with methanol and dried to give 6-(1,3-dioxoindan-2-ylidene)-2-oxo-3-(4-amino-3,5-dimethylphenyl)-2,6-dihydrobenzofuran (0.9 parts, 38%), m.pt. >250° C. λmax (CH2Cl2)=656nm.

출처 및 근거

DOI	10.6084/m9.figshare.5104873.v1
특허 번호	US05268490
출처 데이터셋	uspto-grants-1993_12
ORD ID	ord-c3c6f2fe10d64a5db16f7edfb37b40f6
출처 메모	uspto-grants-1993_12