참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 4-Methoxybenzenesulfonyl chloride | HCID 7401 | — |
| 반응물 | Ammonium Hydroxide | HCID 14923 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 4-Methoxybenzenesulfonamide | HCID 70789 | — |
반응 단계
25 ml of 25% NH4OH were added dropwise while cooling in an ice bath to a solution of 7.3 g of p-methoxybenzenesulfonyl chloride in 50 ml of tetrahydrofuran. Subsequently, the reaction mixture was stirred vigorously for 30 minutes at 70° C. (bath temperature). Thereafter, the tetrahydrofuran was distilled. The residue was extracted with ethyl acetate. There was obtained p-methoxybenzenesulfonamide which was converted into the potassium salt as described in Example 50.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05270313 |
|---|
| 출처 데이터셋 | uspto-grants-1993_12 |
|---|
| ORD ID | ord-951efbaa19c74b62ab9164d05a2e3923 |
|---|
| 출처 메모 | uspto-grants-1993_12 |
|---|
