Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Formamidine → 5-(o-chlorobenzyl)-6-hydroxy-4(3H)-pyrimidinone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Formamidine | HCID 68047 | — |
| 반응물 | Diethyl 2-(2-chlorobenzyl)malonate | HCID 12661049 | — |
| 생성물 | 5-(o-chlorobenzyl)-6-hydroxy-4(3H)-pyrimidinone | HCID 19735337 | — |
반응 단계
Condensation of diethyl o-chlorobenzylmalonate with formamidine yielded 5-(o-chlorobenzyl)-6-hydroxy-4(3H)-pyrimidinone which, by reaction with phosphorus oxychloride, yielded 4,6-chloro-5-(o-chlorobenzyl)pyrimidine, melting point 110°-112° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05270313 |
| 출처 데이터셋 | uspto-grants-1993_12 |
| ORD ID | ord-938cb0896f2a4a44bf376abc087d4d14 |
| 출처 메모 | uspto-grants-1993_12 |