Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethyl Acetate → 4-Amino-2-[(2,2,2-trifluoroethoxy)methyl]pteridine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethyl Acetate | HCID 8857 | — |
| 반응물 | 3-Aminopyrazine-2-carbonitrile | HCID 817699 | — |
| 반응물 | 2-(2,2,2-Trifluoroethoxy)acetamidine | HCID 10583013 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 4-Amino-2-[(2,2,2-trifluoroethoxy)methyl]pteridine | HCID 10539187 | — |
반응 단계
Obtained using the procedure described in section c of Example 2, starting with 7.2 g (0.060 mole) of 3-amino-2-pyrazinecarbonitrile and 14.2 g (0.091 mole) of 2-(2,2,2-trifluoroethoxy)acetamidine in 230 ml of absolute ethanol. Refluxing time: 7 hours. Yld: 6.5 g (42%), m p. 145°-147° C. (ethyl acetate).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05270465 |
| 출처 데이터셋 | uspto-grants-1993_12 |
| ORD ID | ord-276bc173ceef417b98d7a35107a2fbe0 |
| 출처 메모 | uspto-grants-1993_12 |