Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethyl Acetate → 2-[(2,2,2-Trifluoroethoxy)methyl]-4(3H)-pteridinone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethyl Acetate | HCID 8857 | — |
| 반응물 | 4-Amino-2-[(2,2,2-trifluoroethoxy)methyl]pteridine | HCID 10539187 | — |
| 용매 | Sodium Hydroxide | HCID 14798 | — |
| 생성물 | 2-[(2,2,2-Trifluoroethoxy)methyl]-4(3H)-pteridinone | HCID 135417224 | — |
반응 단계
Obtained using the procedure described in section d of Example 2, starting with 5.0 g (0.0193 mole) of 4-amino-2-[(2,2,2-trifluoroethoxy)methyl]pteridine in 105 ml of 5% aqueous sodium hydroxide. Heating time: 1 hour 30 minutes at 80° C. Yld: 2.5 g (50%), m.p. 165°-167° C. (ethyl acetate).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05270465 |
| 출처 데이터셋 | uspto-grants-1993_12 |
| ORD ID | ord-45bbbca9bbf049fd95e47657fcfd4123 |
| 출처 메모 | uspto-grants-1993_12 |