1-(3-Fluoro-4-piperazin-1-ylphenyl)ethanone → HCID 41770750, 화합물

HRID 32699

반응식

HRID 32699 반응식
[F:1][C:2]1[CH:3]=[C:4]([C:14](=[O:16])[CH3:15])[CH:5]=[CH:6][C:7]=1[N:8]1[CH2:13][CH2:12][NH:11][CH2:10][CH2:9]1.[Cl:17][C:18]1[CH:26]=[CH:25][C:24]([S:27](=[O:32])(=[O:31])[N:28]([CH3:30])[CH3:29])=[CH:23][C:19]=1[C:20](O)=[O:21]>>[C:14]([C:4]1[CH:5]=[CH:6][C:7]([N:8]2[CH2:13][CH2:12][N:11]([C:20]([C:19]3[CH:23]=[C:24]([S:27]([N:28]([CH3:30])[CH3:29])(=[O:32])=[O:31])[CH:25]=[CH:26][C:18]=3[Cl:17])=[O:21])[CH2:10][CH2:9]2)=[C:2]([F:1])[CH:3]=1)(=[O:16])[CH3:15]

참가 물질

3

반응물 2

HCID 6856101-(3-Fluoro-4-piperazin-1-ylphenyl)ethanoneHCID 23247842-Chloro-5-(dimethylsulfamoyl)benzoic acid

생성물 1

HCID 41770750HCID 41770750, 화합물

실험 절차

The title compound was prepared according to the procedure described for example K/step2 from 1-(3-Fluoro-4-piperazin-1-yl-phenyl)-ethanone and 2-Chloro-5-dimethylsulfamoyl-benzoic acid (CAS: 37088-27-0; BE 620741) (64%, light yellow foam, MS (m/e): 468.1 (M+H+, 100%)

출처 및 근거

ORD 기록
ord-fb34a088c9ed487683f859ea7c406baf
출처 데이터셋
uspto-grants-2008_09
특허 번호
US07427612B2

연결된 노트

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