4-Amino-1-methyl-3-propyl-1H-pyrazole-5-carboxamide → 4-(5-Acetyl-2-ethoxybenzamido)-1-methyl-3-n-propylpyrazole-5-carboxamide

HRID 327071

반응식

HRID 327071 반응식
[C:1]([C:4]1[CH:5]=[CH:6][C:7]([O:13][CH2:14][CH3:15])=[C:8]([CH:12]=1)[C:9](Cl)=[O:10])(=[O:3])[CH3:2].[NH2:16][C:17]1[C:18]([CH2:26][CH2:27][CH3:28])=[N:19][N:20]([CH3:25])[C:21]=1[C:22]([NH2:24])=[O:23]>>[C:1]([C:4]1[CH:5]=[CH:6][C:7]([O:13][CH2:14][CH3:15])=[C:8]([CH:12]=1)[C:9]([NH:16][C:17]1[C:18]([CH2:26][CH2:27][CH3:28])=[N:19][N:20]([CH3:25])[C:21]=1[C:22]([NH2:24])=[O:23])=[O:10])(=[O:3])[CH3:2]

참가 물질

3

반응물 2

HCID 33380444-Amino-1-methyl-3-propyl-1H-pyrazole-5-carboxamideHCID 212508125-Acetyl-2-ethoxybenzoyl chloride

생성물 1

HCID 539584074-(5-Acetyl-2-ethoxybenzamido)-1-methyl-3-n-propylpyrazole-5-carboxamide

실험 절차

The title compound was prepared form 5-acetyl-2-ethoxybenzoyl chloride and 4-amino-1-methyl-3-n-propylpyrazole-5-carboxamide following the procedure of Preparation 6, and was obtained as a white solid (60%), m.p. 225°-227° C. Found: C,61.35; H,6.25; N,15.07. C19H24N4O4 requires C,61.28; H,6.50; N,15.04%

후처리

  1. customthe procedure of Preparation 6

출처 및 근거

ORD 기록
ord-9128faef0ac1461897886d2ec28e000e
출처 데이터셋
uspto-grants-1993_12
특허 번호
US05272147

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