1-Bromo-4-(methylsulphonyl)benzene → 4-(4-Methanesulfonyl-phenyl)piperazine-1-carboxylic acid tert-butyl ester

HRID 32708

반응식

HRID 32708 반응식
[CH3:1][S:2]([C:5]1[CH:10]=[CH:9][C:8](Br)=[CH:7][CH:6]=1)(=[O:4])=[O:3].[C:12]([N:19]1[CH2:24][CH2:23][NH:22][CH2:21][CH2:20]1)([O:14][C:15]([CH3:18])([CH3:17])[CH3:16])=[O:13]>>[C:15]([O:14][C:12]([N:19]1[CH2:24][CH2:23][N:22]([C:8]2[CH:9]=[CH:10][C:5]([S:2]([CH3:1])(=[O:4])=[O:3])=[CH:6][CH:7]=2)[CH2:21][CH2:20]1)=[O:13])([CH3:18])([CH3:16])[CH3:17]

참가 물질

3

반응물 2

HCID 770141-Bromo-4-(methylsulphonyl)benzeneHCID 143452tert-Butyl piperazine-1-carboxylate

생성물 1

HCID 597935014-(4-Methanesulfonyl-phenyl)piperazine-1-carboxylic acid tert-butyl ester

실험 절차

The title compound was prepared according to the procedure described for example AX from 4-bromophenyl methyl sulfone and N-Boc-piperazine (31%, white solid, MS (m/e): 241.2(M-Boc, 100%)

출처 및 근거

ORD 기록
ord-cbe02993323f47e199ad3f2ba96f5502
출처 데이터셋
uspto-grants-2008_09
특허 번호
US07427612B2

연결된 노트

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