Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Neopentylamine → N-cyano N'-(2,2-dimethylpropyl)-2-pyridinecarboximidamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Neopentylamine | HCID 79882 | — |
| 반응물 | 2-Pyridinecarboximidic acid, N-cyano-, methyl ester | HCID 10012189 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | N-cyano N'-(2,2-dimethylpropyl)-2-pyridinecarboximidamide | HCID 19734543 | 94% |
반응 단계
Methyl N-cyano-2-pyridinecarboximidate (0.50 g, 3.1 mmol) was dissolved in methanol (10 ml), 2,2-dimethylpropylamine (0.30 g, 3.4 mmol) was added, and the resulting mixture was stirred at room temperature for 30 minutes. After the reaction was completed, the reaction solution was concentrated under reduced pressure, and the residue thus obtained was crystallized from dichloromethane-diethyl ether to give the title compound (0.63 g, 2.9 mmol, yield: 94%) as colorless needles.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05272164 |
| 출처 데이터셋 | uspto-grants-1993_12 |
| ORD ID | ord-54fcd94988754977916ff5c504f1ffa1 |
| 출처 메모 | uspto-grants-1993_12 |