Morpholine → 1-{4-[4-(2-Morpholin-4-yl-5-nitro-benzoyl)-piperazin-1-yl]-phenyl}-ethanone

HRID 32712

반응식

HRID 32712 반응식
F[C:2]1[CH:24]=[CH:23][C:22]([N+:25]([O-:27])=[O:26])=[CH:21][C:3]=1[C:4]([N:6]1[CH2:11][CH2:10][N:9]([C:12]2[CH:17]=[CH:16][C:15]([C:18](=[O:20])[CH3:19])=[CH:14][CH:13]=2)[CH2:8][CH2:7]1)=[O:5].[NH:28]1[CH2:33][CH2:32][O:31][CH2:30][CH2:29]1>>[N:28]1([C:2]2[CH:24]=[CH:23][C:22]([N+:25]([O-:27])=[O:26])=[CH:21][C:3]=2[C:4]([N:6]2[CH2:11][CH2:10][N:9]([C:12]3[CH:17]=[CH:16][C:15]([C:18](=[O:20])[CH3:19])=[CH:14][CH:13]=3)[CH2:8][CH2:7]2)=[O:5])[CH2:33][CH2:32][O:31][CH2:30][CH2:29]1

참가 물질

3

반응물 2

HCID 8083MorpholineHCID 597935401-{4-[4-(2-Fluoro-5-nitro-benzoyl)-piperazin-1-yl]-phenyl}-ethanone

생성물 1

HCID 597935881-{4-[4-(2-Morpholin-4-yl-5-nitro-benzoyl)-piperazin-1-yl]-phenyl}-ethanone

실험 절차

The title compound was prepared according to the procedure described for example 1 from 1-{4-[4-(2-Fluoro-5-nitro-benzoyl)-piperazin-1-yl]-phenyl}-ethanone and morpholine (85%, yellow solid, MS (m/e): 439.3 (M+H, 100%)

출처 및 근거

ORD 기록
ord-43252a60f98a4996aacd9f53e22e6840
출처 데이터셋
uspto-grants-2008_09
특허 번호
US07427612B2

연결된 노트

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