Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Phenethylamine → N-cyano-N'-(2-phenylethyl)-2-thiophenecarboximidamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Phenethylamine | HCID 1001 | — |
| 반응물 | 2-Thiophenecarboximidic acid, N-cyano-, methyl ester | HCID 10241147 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | N-cyano-N'-(2-phenylethyl)-2-thiophenecarboximidamide | HCID 19734476 | 98.5% |
반응 단계
Methyl N-cyano-2-thiophenecarboximidate (0.33 g, 2.0 mmol) was dissolved in methanol (2 ml), and 2-phenylethylamine (0.27 g, 2.2 mmol) was added. The mixture was stirred at room temperature for 1 hour. After the reaction was completed, the reaction solution was concentrated under reduced pressure, and the residue thus obtained was crystallized from diethyl ether-hexane to give the title compound (0.50 g, 1.97 mmol, yield: 98%) as colorless crystals.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05272164 |
| 출처 데이터셋 | uspto-grants-1993_12 |
| ORD ID | ord-8136a204aacb4d8c85cb2c9a19a44b8e |
| 출처 메모 | uspto-grants-1993_12 |