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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 327135생성일: 2026년 10월 26일

Phenethylamine → N-cyano-N'-(2-phenylethyl)-2-thiophenecarboximidamide

https://huagongshe.com/reaction/327135

반응식

참여 물질

역할이름HCID투입량
반응물PhenethylamineHCID 1001—
반응물2-Thiophenecarboximidic acid, N-cyano-, methyl esterHCID 10241147—
용매MethanolHCID 887—
생성물N-cyano-N'-(2-phenylethyl)-2-thiophenecarboximidamideHCID 1973447698.5%

반응 단계

Methyl N-cyano-2-thiophenecarboximidate (0.33 g, 2.0 mmol) was dissolved in methanol (2 ml), and 2-phenylethylamine (0.27 g, 2.2 mmol) was added. The mixture was stirred at room temperature for 1 hour. After the reaction was completed, the reaction solution was concentrated under reduced pressure, and the residue thus obtained was crystallized from diethyl ether-hexane to give the title compound (0.50 g, 1.97 mmol, yield: 98%) as colorless crystals.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US05272164
출처 데이터셋uspto-grants-1993_12
ORD IDord-8136a204aacb4d8c85cb2c9a19a44b8e
출처 메모uspto-grants-1993_12