1-(4-Chlorophenyl)piperazine → (4-(4-Chlorophenyl)piperazin-1-yl)(2-morpholino-5-nitrophenyl)methanone

HRID 32717

반응식

HRID 32717 반응식
[N:1]1([C:7]2[CH:15]=[CH:14][C:13]([N+:16]([O-:18])=[O:17])=[CH:12][C:8]=2[C:9](Cl)=[O:10])[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1.[Cl:19][C:20]1[CH:25]=[CH:24][C:23]([N:26]2[CH2:31][CH2:30][NH:29][CH2:28][CH2:27]2)=[CH:22][CH:21]=1>>[Cl:19][C:20]1[CH:21]=[CH:22][C:23]([N:26]2[CH2:31][CH2:30][N:29]([C:9]([C:8]3[CH:12]=[C:13]([N+:16]([O-:18])=[O:17])[CH:14]=[CH:15][C:7]=3[N:1]3[CH2:6][CH2:5][O:4][CH2:3][CH2:2]3)=[O:10])[CH2:28][CH2:27]2)=[CH:24][CH:25]=1

참가 물질

3

반응물 2

HCID 974781-(4-Chlorophenyl)piperazineHCID 172741532-Morpholin-4-yl-5-nitro-benzoyl chloride

생성물 1

HCID 44580261(4-(4-Chlorophenyl)piperazin-1-yl)(2-morpholino-5-nitrophenyl)methanone

실험 절차

The title compound was prepared according to the procedure described for example 46 from 2-morpholin-4-yl-5-nitro-benzoyl chloride and 4-chloro-phenyl-piperazine (orange solid), MS (m/e): 449.2 (M+H, 100%).

출처 및 근거

ORD 기록
ord-5c2ecf8cbfc543e98877039ca1c1843b
출처 데이터셋
uspto-grants-2008_09
특허 번호
US07427612B2

연결된 노트

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