Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Chloro-5-aminosulfonylbenzoic acid → 3-[4-(4-Acetyl-2-fluoro-phenyl)-piperazine-1-carbonyl]-4-chloro-benzenesulfonamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Chloro-5-aminosulfonylbenzoic acid | HCID 66794 | — |
| 반응물 | 1-(3-Fluoro-4-piperazin-1-ylphenyl)ethanone | HCID 685610 | — |
| 생성물 | 3-[4-(4-Acetyl-2-fluoro-phenyl)-piperazine-1-carbonyl]-4-chloro-benzenesulfonamide | HCID 36807410 | — |
반응 단계
The title compound was prepared according to the procedure described for example K/step2 from 1-(3-Fluoro-4-piperazin-1-yl-phenyl)-ethanone and 2-Chloro-5-sulfamoyl-benzoic acid (CAS: 97-04-1; Basu; D.-G.; J.Indian Chem.Soc.; 16; 1939; 100, 106) (42%, white solid), MS (m/e): 438.1 (M−H, 100%)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07427612B2 |
| 출처 데이터셋 | uspto-grants-2008_09 |
| ORD ID | ord-26ab8df88ac24ac5b8a1a558a748f8aa |
| 출처 메모 | uspto-grants-2008_09 |