Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Iodine → 2-Propyl-3-t-butyl-4-hydroxy-5-isopropylphenol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Iodine | HCID 807 | — |
| 반응물 | 1,1,3,3-Tetramethyl-disiloxane | HCID 18659 | — |
| 반응물 | 2-Propyl-3-t-butyl-5-isopropylbenzoquinone | HCID 57066423 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 2-Propyl-3-t-butyl-4-hydroxy-5-isopropylphenol | HCID 54017886 | — |
반응 단계
Dissolve 2-propyl-3-t-butyl-5-isopropylbenzoquinone (10mmol), 1,1,3,3-tetramethyldisiloxane (1.79mL, 10mmol) and iodine (0.05g) in methylene chloride (30mL). Stir at reflux for 30 minutes and extract with 1N sodium hydroxide (30mL). Acidify the aqueous phase with concentrated hydrochloric acid and extract into ethyl acetate (4×10mL), dry (NazSO4) and evaporate the solvent in vacuo to give 2-propyl-3-t-butyl-4-hydroxy-5-isopropylphenol.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05272252 |
| 출처 데이터셋 | uspto-grants-1993_12 |
| ORD ID | ord-b46a9b0399e14315810fcbac9dd0be5b |
| 출처 메모 | uspto-grants-1993_12 |