1-(3,5-Difluorophenyl)pentan-1-ol → 1,3-Difluoro-5-(pent-1-en-1-yl)benzene

HRID 327371노트

반응식

HRID 327371 반응식
[P+3]=O.[F:3][C:4]1[CH:9]=[C:8]([CH:10](O)[CH2:11][CH2:12][CH2:13][CH3:14])[CH:7]=[C:6]([F:16])[CH:5]=1>CCCCC>[F:3][C:4]1[CH:9]=[C:8]([CH:10]=[CH:11][CH2:12][CH2:13][CH3:14])[CH:7]=[C:6]([F:16])[CH:5]=1

참가 물질

4

반응물 2

HCID 225984431-(3,5-Difluorophenyl)pentan-1-olHCID 178526999HCID 178526999, 화합물

생성물 1

HCID 536320701,3-Difluoro-5-(pent-1-en-1-yl)benzene

시약·촉매·용매 1

HCID 8003Pentane용매

실험 절차

Phosphorus(v) oxide (64.5 g, 0.45 mol) is added to a stirred solution of compound 9A (35.0 g, 0.175 mol) in dry pentane (150 ml) at room temperature. The mixture is stirred at room temperature overnight (glc analysis revealed absence of starting material) and filtered.

후처리

  1. filtrationfiltered

출처 및 근거

ORD 기록
ord-82692c8c00af4fbca90d5793d6c3a70f
출처 데이터셋
uspto-grants-1993_12
특허 번호
US05273680

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