Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 3,4,5-Trimethoxyphenylacetic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | 3,4,5-Trimethoxyphenylacetonitrile | HCID 25887 | — |
| 반응물 | Methanol--water (1/1) | HCID 22242641 | — |
| 생성물 | 3,4,5-Trimethoxyphenylacetic acid | HCID 70372 | — |
반응 단계
3,4,5-trimethoxyphenyl acetonitrile 5.5 g was dissolved into 50 ml of methanol/water (9:1). To this 1 .5 g of sodium hydroxide was added and they were then stirred and refluxed for 5.5 hours. The temperature of the reactive liquid was lowered down to room temperature and neutralized with 2N hydrochloric acid, and the methanol was distilled off under reduced pressure. Extraction was performed thrice by means of 100 ml of chloroform. After distilling off the solvent under reduced pressure, 5.8 g of captioned compound was obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05273985 |
| 출처 데이터셋 | uspto-grants-1993_12 |
| ORD ID | ord-e7187962b89b4a35b63770f24bc46a23 |
| 출처 메모 | uspto-grants-1993_12 |