Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Cyclopropanemethanamine → [2-(Cyclopropylmethyl-amino)-5-methanesulfonyl-phenyl]-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-methanone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Cyclopropanemethanamine | HCID 75646 | — |
| 반응물 | (2-Iodo-5-methanesulfonyl-phenyl)-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-methanone | HCID 59793691 | — |
| 생성물 | [2-(Cyclopropylmethyl-amino)-5-methanesulfonyl-phenyl]-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-methanone | HCID 68839612 | 40% |
반응 단계
The title compound was prepared according to the procedure described for example 301 from (2-Iodo-5-methanesulfonyl-phenyl)-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-methanone (compound CK) and Cyclopropanemethylamine (40% yield, white foam, MS (m/e): 482.5 (M+H, 100%)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07427612B2 |
| 출처 데이터셋 | uspto-grants-2008_09 |
| ORD ID | ord-4de433ffe56143aa8ee1840fef8806a6 |
| 출처 메모 | uspto-grants-2008_09 |