1,5-Dibromopentane → 5-[(5-Bromopentyl)oxy]-2-benzofurancarboxylic Acid Ethyl Ester

HRID 327950

반응식

HRID 327950 반응식
[CH2:1]([O:3][C:4]([C:6]1[O:7][C:8]2[CH:14]=[CH:13][C:12]([OH:15])=[CH:11][C:9]=2[CH:10]=1)=[O:5])[CH3:2].[Br:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21]Br>>[CH2:1]([O:3][C:4]([C:6]1[O:7][C:8]2[CH:14]=[CH:13][C:12]([O:15][CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][Br:16])=[CH:11][C:9]=2[CH:10]=1)=[O:5])[CH3:2]

참가 물질

3

반응물 2

HCID 81001,5-DibromopentaneHCID 22228632Ethyl 5-hydroxybenzofuran-2-carboxylate

생성물 1

HCID 538030785-[(5-Bromopentyl)oxy]-2-benzofurancarboxylic Acid Ethyl Ester수율 73%

실험 절차

Starting with 2.41 g (11.69 mmol) of 5-hydroxy-2-benzofuran-carboxylic acid ethyl ester, and 8.06 (35.06 mmol) of 1,5-dibromopentane, the title compound (3.03 g; 73%) was obtained as a white solid, mp 31° C., using the procedure of example 21.

출처 및 근거

ORD 기록
ord-ecee3c272b8b4bacb446828d1acc4f9e
출처 데이터셋
uspto-grants-1993_12
특허 번호
US05273999

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