참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Hydrogen iodide | HCID 24841 | — |
| 반응물 | p-Methoxyphenylpropionic acid | HCID 257576 | — |
| 반응물 | 2-(3-Nitro-4-hydroxyphenyl)propionate | HCID 21444170 | — |
| 생성물 | 2-(4-Hydroxyphenyl)propionic acid | HCID 102526 | — |
반응 단계
Also, the compounds (III) used for this invention, for example, 2-(3-nitro-4-hydroxyphenyl)propionate can be prepared by demethylating 2-(4-methoxyphenyl)propionic acid with hydroiodic acid and the like to obtain 2-(4-hydroxyphenyl)- propionic acid, by esterifying the above compound with an usual method to obtain, for example, methyl 2-(4-hydroxyphenyl)propionate and by nitrating the above compounds. Alternately, 2-(3-nitro-4-hydroxyphenyl)propionate can be prepared by nitrating the above 2-(4-hydroxyphenyl)propionic acid with an usual method and by esterificating the resultant compound. The above reactions can be applied to 4-hydroxyphenylacetate as well. The above reaction scheme is shown as follows: ##STR12## wherein R1 has the same meaning as above
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 특허 번호 | US04016193 |
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| 출처 데이터셋 | uspto-grants-1977_04 |
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| ORD ID | ord-76fb6a47486b484f804636832dc37f70 |
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| 출처 메모 | uspto-grants-1977_04 |
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