Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Cytidine Diphosphate → 4-hydroxy-1-beta-D-ribofuranosyl-tetrahydro-2(1H)-pyrimidinone uridine 5'-diphosphate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Cytidine Diphosphate | HCID 6132 | — |
| 반응물 | Ammonium Hydroxide | HCID 14923 | — |
| 촉매 | Rhodium | HCID 23948 | — |
| 생성물 | 4-hydroxy-1-beta-D-ribofuranosyl-tetrahydro-2(1H)-pyrimidinone uridine 5'-diphosphate | HCID 86734645 | — |
반응 단계
In the manner given in Example 2D, cytidine 5'-diphosphate was hydrogenated in dilute ammonium hydroxide in the presence of a rhodium on alumina catalyst, and the mixture separated with a Craig extractor to give 4-hydroxy-1-β-D-ribofuranosyl-tetrahydro-2(1H)-pyrimidinone uridine 5'-diphosphate and 1-β-D-ribofuranosyl-tetrahydro-2(1H)-pyrimidinone 5'-diphosphate.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04017606 |
| 출처 데이터셋 | uspto-grants-1977_04 |
| ORD ID | ord-f4a534c9938a426c81e57cbe69dbea59 |
| 출처 메모 | uspto-grants-1977_04 |